Meanwhile, the UN rescues Palmer Eldritch's ship from a crash on Pluto. Leo Bulero, head of P.P. Layouts and an "evolved" human (meaning someone who has undergone expensive genetic treatments by a German "doctor" which are supposed to push the client "forward" on an evolutionary scale, and which result in gross physical, as well as mental, modifications), hears rumors that Eldritch discovered an alien hallucinogen in the Prox system with similar properties to CAN-D, and that he plans to market it as "Chew-Z," with UN approval, on off-world colonies. However CHEW-Z does not require the prop of the external layouts and seems to have certain undefined qualities that make the use of CHEW-Z even more addictive than CAN-D has been. This would effectively destroy P.P. Layouts. Bulero tries to contact Eldritch but he is quarantined at a UN hospital. Both Mayerson and Fugate have precognitions of reports that Bulero is going to be responsible for murdering Eldritch.
Meanwhile, Emily and her second husband sell her pottery designs to Eldritch and use the payment to undergo evolution therapy. Unfortunately, Emily begins to devolve rather than evolving. This devolution results in a loss of creativity and she finds herself recreating older, less sophisticated designs from earlier work, without realizing it.
Under the guise of a reporter, Bulero travels to Eldritch's estate on the Moon, where Eldritch holds a press conference. Bulero is kidnapped and forced to take Chew-Z intravenously. He enters a psychic netherworld over which both he and Eldritch seemingly have some control. After wrangling about business with Eldritch, Bulero travels to what appears to be Earth at some time in the not-too-distant future. Evolved humans identify him as a ghost and show him a monument to himself commemorating his role in the death of Eldritch, an "enemy of the Sol System."
Bulero returns to Earth and fires Mayerson because Mayerson was afraid to travel to the Moon to rescue him. Mayerson, in despair, accepts his UN conscription to Mars but Bulero recruits him as a double agent. Mayerson is to inject himself with a toxin after taking Chew-Z in a plot to deceive the UN into thinking Chew-Z is harmful and cause them to ban it.
On Mars, Mayerson buys some Chew-Z from Eldritch, who appears in holographic form. Mayerson tries to hallucinate a world where he is still with Emily but finds that he does not control his apparent hallucination. Like Bulero, he finds himself in the future. Mayerson arrives in New York two years hence where he speaks with Bulero, Fugate and his future self about the death of Palmer Eldritch.